What is ICSI – Intra-Cytoplasmic Sperm Injection?
Intra-Cytoplasmic Sperm Injection (ICSI) is used in cases of male subfertility or previous failed fertilisation with IVF. A single sperm is selected and injected directly into the egg using special equipment called a Micromanipulator. In these situations, clearly very few sperm are required and a fine needle is used to inject the Sperm inside each egg. It is however important to recognise that ICSI does not guarantee fertilisation.
The processes of ovulation induction and egg collection as for routine IVF are also required. Only mature eggs are suitable for ICSI, this can only be confirmed after assessing the eggs under the microscope, in very rare cases, none of the eggs may be suitable for ICSI.
A fertilisation rate of 60% is expected by using the ICSI technique. However, the ICSI procedure carries a small risk of damaging the egg during the actual sperm injection. The risk is minimal at about 10% and will be evident at the time of the injection, and these eggs will not be used for the treatment. The fertilised eggs then develop as per the standard IVF treatment.
Who can benefit from ICSI?
Newlife recommends ICSI if:
- you have a very low sperm count
- other problems with the sperm have been identified, such as poor morphology (abnormal shape) or poor motility (not moving normally)
- during previous attempts at IVF there was failure of fertilisation or an unexpectedly low fertilisation rate
- you need sperm to be collected surgically from the testicles or epididymis (a narrow tube inside the scrotum, where sperm are stored and matured); for example because you have had a vasectomy, you do not ejaculate sperm, or because you have extremely low sperm production
- you are using frozen sperm in your treatment which is not of optimum quality
- you are using embryo testing
What is included in your ICSI treatment cycle fee?
- All monitoring cycle scans whilst in treatment
- Doctor’s fees (excluding Initial consultation fee)
- Standard Embryology laboratory services
- Theatre procedures (Egg collection and Embryo Transfer)
- Anaesthetist charges (Egg collection only)
- Post-op recovery where needed
- 1st Pregnancy blood test
- Follow-up appointment (if the treatment fails)
HFEA Fee and medication are charged separately.