There is currently much debate among the scientific community about the role of the immune system in promoting or preventing healthy pregnancy. Our view, on the evidence of over 10 years’ experience, is that the products of an activated immune system can damage the placenta and cause miscarriage, as well as damage the embryo and cause implantation failure.
Natural killer cells, which help to keep the body from developing cancer, can over-populate the uterus or exist at too high levels within the blood stream. These cells then go overboard, killing the embryo or interfering with the endocrine system that produces the hormones that are essential for pregnancy.
We can carry out a comprehensive group of tests to check different aspects of your immune system and related clotting factors (thrombophilia). These include testing for: Antibodies, Natural Killer Cell Assay, TH1/TH2 Intracellular Cytokine Ratio, Factor V and MTHFR, Leukocyte Antibody Detection (LAD) or Paternal Leukocyte Antibodies (PLA) and DQa genes.
Once we have identified the problem, we can provide relevant supportive immune therapy, which can include Steroids, Clexane, IVIg and Intralipid.
For more information and guidance from the HFEA please follow this link: Immunological tests | HFEA